WebbOther sites exhibiting decreased phosphorylation have sequences similar to those of canonical PLK1 and AURKB phosphorylation motifs (2, 24). We did not detect increased phosphorylation at SQ sites associated with the DNA damage–activated kinases ATM and ATR ( 24 ), which suggests that OGT overexpression and the synchronization methods … Webb1 dec. 2024 · The expression of AURKB was found to be higher in HCC than in a control and was consistently correlated with patient tumor stage [125]. ... and PLK1 pathways. These results support the idea that hepatitis viruses deregulate the cell cycle in infected cells to promote an environment that can sustain viral replication.
AURKA and PLK1 inhibition selectively and synergistically block …
Webb10 jan. 2024 · The mitotic kinases polo-like kinase 1 (PLK1) and Aurora B (AURKB) phosphorylate survivin, an inhibitor of apoptosis (IAP) family member, thereby regulating … Webb6 juni 2024 · Mycosis fungoides (MF) is the most prevalent type of skin lymphoma. In its early stages, it has a favorable prognosis. However, in its late stages, it is associated with an increased risk of mortality. This systematic review aimed to identify the transcriptomic changes involved in MF pathogenesis and progression. A literature search was … softball black and white png
(PDF) Bioinformatics Analysis Confirms the Target Protein …
Webb4 okt. 2012 · Preliminary analysis of the expression patterns of FOXM1 and its target genes PLK1, CCNB1, AURKB and CKS1 demonstrated a close correlation of their expression … Webb10 jan. 2024 · The mitotic kinases polo-like kinase 1 (PLK1) and Aurora B (AURKB) phosphorylate survivin, an inhibitor of apoptosis (IAP) family member, thereby regulating … Webb10 feb. 2024 · AURKB was capable of activating PLK1 in the M phase of the cell cycle (Archambault and Carmena, 2012), raising the possibility that AURKB regulation of MYC could be indirectly through PLK1. To evaluate this, we respectively treated KOPTK1 cells with PLK1 inhibitor BI6727 or AURKB inhibitor AZD1152. softball camps in ohio 2022