WebFeb 28, 2024 · SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo Mitochondrial dysregulation has been implicated in oxidative stress-induced melanocyte destruction in vitiligo. However, the molecular mechanism underlying this process is merely investigated. WebIn addition, we found that PCr rescued SIRT3 protein level in GS co-treated cells. The expression level of Ac-SOD2 was reduced, and SOD2 activity was partially restored. These findings suggested that PCr inhibited mitochondrial ROS production and rescued cells from apoptosis through the SIRT3-SOD2 pathway. However, these findings require ...
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and ... - PNAS
WebAug 30, 2024 · SIRT3, a member of the silent information regulator (Sirtuins) family, participates in cell biological functions such as energy metabolism and cell aging by regulating mitochondrial function, and it is closely related to tumor development and progression [4–6]. WebAug 3, 2009 · We demonstrate that SIRT3 is a stress-responsive deacetylase that blocks the cardiac hypertrophic response through activation of Foxo-dependent antioxidants, … list of internal departments scp
Sirt3抑制血管紧张素Ⅱ诱导的小鼠血管平滑肌细胞增殖 - 百度学术
WebMar 12, 2024 · SIRT3 deficiency resulted in the detachment of genomic lamina-associated domains (LADs) from the nuclear lamina, increased chromatin accessibility and aberrant … Web万方 知网 维普网 万方医学 《细胞与分子免疫学杂志》官网 查看更多 钛学术 (全网免费下载) journal.9med.net 钛学术 WebFeb 2, 2016 · PGC-1α/ERRα-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase β - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil. list of intermediate skills